1. In Patient Case 1, which of the following recommendations would provide Beth, who has knee osteoarthritis (OA), with the most effective treatment option that is also safe for her to use considering her comorbidities/risks?  CASE 1

2. In Patient Case 1, Beth admits to drinking more than 1 glass of wine with dinner each night and that she has an aspirin allergy she previously failed to disclose. In light of this new information, which over-the-counter (OTC) treatment remains an appropriate option for her?

3. In Patient Case 2, what OTC option would you recommend to Bill, who has OA in his hands and knees, with respect to his preference for an oral formulation?  CASE 2

4. In Patient Case 2, following a discussion with Bill about the risks versus benefits associated with oral therapy, he informs you that he tried topical diclofenac that morning and did not perceive any benefit. He clarifies that is why he is not interested in continuing the diclofenac. Which of the following options should be discussed with Bill?

5. In Patient Case 3, which of the following prescription therapies would be most appropriate for Emily, who has knee OA, to consider at this time?  CASE 3

6. In Patient Case 3, Emily is doing well with her current treatment regimen, but she has days that she would like to take something for breakthrough pain. She is not looking to add something as a daily treatment option but would like advice on what to take occasionally when her joints are aching, such as on rainy or overly active days. She recalls that her primary care provider recommended she discontinue ibuprofen, and she also no longer perceived any benefit from acetaminophen. Of the following options, should Emily take an OTC medication, or does she need to get a prescription?

7. A 70-year-old woman asks you to recommend which topical capsaicin product she should initiate for the treatment of her knee OA. Which of the following would be the best option for this patient?

8. Dan is a 55-year-old man that was recently diagnosed with hip OA. He lives in a small rural community 1 hour away from the city. Which of the following nonpharmacological options may be best to recommend for Dan?

9. Which OTC medication option is strongly recommended across both OA guidelines, regardless of comorbidities and frailty?

10. What monitoring parameter is achievable for a pharmacist to provide for patients utilizing chronic oral NSAIDs?

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