1. What is the minimum time until HIV protection is achieved in the rectal tissue with daily FTC/TDF PrEP use?

2. How often must patients be screened for HIV while on PrEP?

3. Which of the following is a side effect requiring monitoring while on PrEP?

4. When used appropriately, how effective is PrEP at reducing HIV acquisition?

5. Please consider the following CASE:
Michael is a 19-year-old, African American gay male who presents to urgent care complaining of fever and malaise x 7 days.  On physical exam, a nonspecific rash was noted on his trunk.

Past Medical History:
n/a
Social History: He is sexually active however he is not in a monogamous relationship; last high risk sexual encounter was 3 weeks ago and reports 6 anonymous partners in the last 3 months with inconsistent condom use; smokes ½ pack per day x 1 year; binge drinks only on the weekends; denies illicit drug use; works as a waiter in New York City.
Medications: None
Allergies: No Known Drug Allergies
Vitals: Blood Pressure 106/72      Pulse 108      Temperature 101 F
Glomerular Filtration Rate  > 60

Based on Michael's presentation, what is the preferred next step?

6. Which of the following is CORRECT regarding post-exposure prophylaxis for HIV?

7. When is HIV testing recommended for post-exposure prophylaxis?

8. In the case of nPEP, which of the following is the most accurate regarding the source patient?

9. Which of the following regimens is recommended for nPEP for a 23-year-old individual of child bearing potential?

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